Name :
Recombinant Human CXCR4 Protein, GST-tagged
Specification :
| Description : This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 64.46 kDa | AA Sequence : MEGISIYTSDNYTEEMGSGDYDSMK EPCFREENANFNKIFLPTIYSIIFL TGIVGNGLVILVMGYQKKLRSMTDK YRLHLSVADLLFVITLPFWAVDAVA NWYFGNFLCKAVHVIYTVNLYSSVL ILAFISLDRYLAIVHATNSQRPRKL LAEKVVYVGVWIPALLLTIPDFIFA NVSEADDRYICDRFYPNDLWVVVFQ FQHIMVGLILPGIVILSCYCIIISK LSHSKGHQKRKALKTTVILILAFFA CWLPYYIGISIDSFILLEIIKQGCE FENTVHKWISITEALAFFHCCLNPI LYAFLGAKFKTSAQHALTSVSRGSS LKILSKGKRGGHSSVSTESESSSFH SS | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Information :
| Gene Name : CXCR4 chemokine (C-X-C motif) receptor 4 [ Homo sapiens ] | Official Symbol : CXCR4 | Synonyms : CXCR4; chemokine (C-X-C motif) receptor 4; chemokine (C X C motif), receptor 4 (fusin); C-X-C chemokine receptor type 4; CD184; D2S201E; fusin; HM89; HSY3RR; LESTR; NPY3R; NPYR; NPYY3R; CXC-R4; CXCR-4; CD184 antigen; SDF-1 receptor; neuropeptide Y receptor Y3; seven transmembrane helix receptor; stromal cell-derived factor 1 receptor; lipopolysaccharide-associated protein 3; seven-transmembrane-segment receptor, spleen; leukocyte-derived seven transmembrane domain receptor; leukocyte-derived seven-transmembrane-domain receptor; FB22; LAP3; LCR1; WHIM; NPYRL; | Gene ID : 7852 | mRNA Refseq : NM_001008540 | Protein Refseq : NP_001008540 | MIM : 162643 | UniProt ID : P61073
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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