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Name :
Recombinant Human IL12RB1 Protein, His-tagged

Specification :
| Description : Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. | Source : E. coli | Species : Human | Tag : His | Molecular Mass : ~52 kDa | AA Sequence : CRTSECCFQDPPYPDADSGSASGPR DLRCYRISSDRYECSWQYEGPTAGV SHFLRCCLSSGRCCYFAAGSATRLQ FSDQAGVSVLYTVTLWVESWARNQT EKSPEVTLQLYNSVKYEPPLGDIKV SKLAGQLRMEWETPDNQVGAEVQFR HRTPSSPWKLGDCGPQDDDTESCLC PLEMNVAQEFQLRRRQLGSQGSSWS KWSSPVCVPPENPPQPQVRFSVEQL GQDGRRRLTLKEQPTQLELPEGCQG LAPGTEVTYRLQLHMLSCPCKAKAT RTLHLGKMPYLSGAAYNVAVISSNQ FGPGLNQTWHIPADTHTEPVALNIS VGTNGTTMYWPARAQSMTYCIEWQP VGQDGGLATCSLTAPQDPDPAGMAT YSWSRESGAMGQEKCYYITIFASAH PEKLTLWSTVLSTYHFGGNASAAGT PHHVSVKNHSLDSVSVDWAPSLLST CPGVLKEYVVRCRDEDSKQVSEHPV QPTETQVTLSGLRAGVAYTVQVRAD TAWLRGVWSQPQRFSIEVQVSD | Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). | Notes : For research use only, not for use in diagnostic procedure. | Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. | Storage Buffer : PBS, 4M Urea, pH7.4

Gene Information :
| Gene Name : IL12RB1 interleukin 12 receptor, beta 1 [ Homo sapiens (human) ] | Official Symbol : IL12RB1 | Synonyms : IL12RB1; interleukin 12 receptor, beta 1; IL12RB; interleukin-12 receptor subunit beta-1; CD212; IL-12RB1; IL-12R-beta-1; IL-12R subunit beta-1; IL-12 receptor beta component; IL-12 receptor subunit beta-1; interleukin-12 receptor beta-1 chain; IL-12R-BETA1; MGC34454; | Gene ID : 3594 | mRNA Refseq : NM_005535 | Protein Refseq : NP_005526 | MIM : 601604 | UniProt ID : P42701

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Author: Cholesterol Absorption Inhibitors