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Name :
Active Recombinant Human FGFR4 protein, hFc&His-tagged

Specification :
| Source : HEK293 | Species : Human | Tag : hFc&His | Form : Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. | Bio-activity : 1.Measured by its binding ability in a functional ELISA. Immobilized recombinant human FGF2 at 1 μg/mL (100 μL/well) can bind recombinant human FGFR4 with a linear range of 30-125 ng/mL.2.Measured by its binding ability in a functional ELISA. Immobilized recombinant human FGFR4 at 5 μg/mL (100 μL/well) can bind recombinant human FGF12 with a linear range of 35-100 ng/mL. 3.Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL. | Molecular Mass : 90-110 kDa | Protein Length : Leu22-Asp369 | Endotoxin : | Purity : > 95% by SDS-PAGE. | Storage : Store the lyophilized protein at -20°C to -80 °C for long term.After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. | Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

Gene Information :
| Gene Name : FGFR4 fibroblast growth factor receptor 4 [ Homo sapiens ] | Official Symbol : FGFR4 | Synonyms : FGFR4; fibroblast growth factor receptor 4; CD334; JTK2; FGFR-4; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; tyrosine kinase related to fibroblast growth factor receptor; TKF; MGC20292; | Gene ID : 2264 | mRNA Refseq : NM_002011 | Protein Refseq : NP_002002 | MIM : 134935 | UniProt ID : P22455

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors