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Name :
Recombinant Human IL17A & IL17F protein, His-Avi-tagged, Biotinylated

Specification :
| Description : Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22um filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 15.1 kDa (Q16552-1) &17.5 kDa (Q96PD4).Due to glycosylation, the protein migrates to 16KDa&27KDa based on Bis-Tris PAGE result. | Protein length : It contains Gly 24 – Ala 155 (IL-17A) & Arg31-Gln163 . | Endotoxin : Less than 0.005EU per ug by the LAL method. | Purity : > 95% as determined by Tris-Bis PAGE; | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information :
| Gene Name : IL17A interleukin 17A [ Homo sapiens ] | Official Symbol : IL17A; IL17F | Synonyms : IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,IL24,ML-1,Interleukin-17F | Gene ID : 3605 | mRNA Refseq : NM_002190 | Protein Refseq : NP_002181 | MIM : 603149 | UniProt ID : Q16552

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors