Name :
Recombinant Human IL17A & IL17F protein, His-Avi-tagged, Biotinylated
Specification :
| Description : Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22um filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 15.1 kDa (Q16552-1) &17.5 kDa (Q96PD4).Due to glycosylation, the protein migrates to 16KDa&27KDa based on Bis-Tris PAGE result. | Protein length : It contains Gly 24 – Ala 155 (IL-17A) & Arg31-Gln163 . | Endotoxin : Less than 0.005EU per ug by the LAL method. | Purity : > 95% as determined by Tris-Bis PAGE; | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Information :
| Gene Name : IL17A interleukin 17A [ Homo sapiens ] | Official Symbol : IL17A; IL17F | Synonyms : IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,IL24,ML-1,Interleukin-17F | Gene ID : 3605 | mRNA Refseq : NM_002190 | Protein Refseq : NP_002181 | MIM : 603149 | UniProt ID : Q16552
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