Name :
Recombinant Human IL17RA Protein (Met1-Trp320), C-His tagged
Specification :
| Description : Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A) . IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F. Ligand and IL 17RA ligation promotes T cell activation and the production of IL – 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) . | Source : Mammalian cells | Species : Human | Tag : C-His | Form : Lyophilized powder/frozen liquid | Molecular Mass : 35.2 kDa | Protein Length : Met1-Trp320 | Endotoxin : | Purity : >90% as determined by SDS-PAGE. | Notes : For research use only. | Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. | Storage Buffer : Supplied as solution form in PBS or lyophilized from PBS. | Reconstitution : Reconstitute in sterile water for a stock solution. | Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Information :
| Gene Name : IL17RA interleukin 17 receptor A [ Homo sapiens (human) ] | Official Symbol : IL17RA | Synonyms : IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262; | Gene ID : 23765 | mRNA Refseq : NM_014339 | Protein Refseq : NP_055154 | MIM : 605461 | UniProt ID : Q96F46
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