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Name :
Recombinant Human IL18R1, His-tagged

Specification :
| Description : The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. | Source : E.coli | Species : Human | Tag : His | Protein length : 1-334a.a. | Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. | Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information :
| Gene Name : IL18R1 interleukin 18 receptor 1 [ Homo sapiens ] | Official Symbol : IL18R1 | Synonyms : IL18R1; interleukin 18 receptor 1; interleukin-18 receptor 1; CD218a; IL 1Rrp; IL1RRP; IL-18R1; IL1R-rp; IL-18R-1; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A; IL18RA; CDw218a; IL-1Rrp; | Gene ID : 8809 | mRNA Refseq : NM_003855 | Protein Refseq : NP_003846 | MIM : 604494 | UniProt ID : Q13478 | Chromosome Location : 2q12 | Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL12 signaling mediated by STAT4, organism-specific biosystem; IL12-mediated signaling events, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; | Function : interleukin-1 receptor activity; receptor activity; transmembrane signaling receptor activity;

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Author: Cholesterol Absorption Inhibitors