Recombinant Human IL18R1, His-tagged

Specification :
| Description : Interleukin-18 receptor 1 (IL18R1) is also known as CD218 antigen-like family member A (CD218a), IL1 receptor-related protein (IL-1Rrp or IL1R-rp), CDw218a, IL18Ra, IL1RRP, which belongs to the interleukin-1 receptor family. IL18R1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL18R1 is receptor for interleukin 18 (IL-18). IL18R1 binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta. | Source : HEK293 | Species : Human | Tag : His | Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. | Molecular Mass : rh IL18R1 /CD218a is fused with polyhistidine tag at the C-terminus, and has a calculated MW of 36.6 kDa. The predicted N-terminus is Ala 19. DTT-reduced Protein migrates as 60-70 kDa in SDS-PAGE due to glycosylation. | Endotoxin : Less than 1.0 EU per μg of the rh IL18R1 /CD218a by the LAL method. | Purity : >95% as determined by SDS-PAGE. | Storage : Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). | Reconstitution : See Certificate of Analysis for reconstitution instructions and specific concentrations.