Recombinant Human IL18R1 Protein, Fc-tagged

Specification :
| Description : The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : Fc | Form : Lyophilized | Molecular Mass : 62.4 kDa | Protein Length : 541 | AA Sequence : MNCRELPLTLWVLISVSTAESCTSR PHITVVEGEPFYLKHCSCSLAHEIE TTTKSWYKSSGSQEHVELNPRSSSR IALHDCVLEFWPVELNDTGSYFFQM KNYTQKWKLNVIRRNKHSCFTERQV TSKIVEVKKFFQITCENSYYQTLVN STSLYKNCKKLLLENNKNPTIKKNA EFEDQGYYSCVHFLHHNGKLFNITK TFNITIVEDRSNIVPVLLGPKLNHV AVELGKNVRLNCSALLNEEDVIYWM FGEENGSDPNIHEEKEMRIMTPEGK WHASKVLRIENIGESNLNVLYNCTV ASTGGTDTKSFILVRKADMADIPGH VFTRGMIIAVLILVAVVCLVTVCVI YRVDLVLFYRHLTRRDETLTDGKTY DAFVSYLKECRPENGEEHTFAVEIL PRVLEKHFGYKLCIFERDVVPGGAV VDEIHSLIEKSRRLIIVLSKSYMSN EVRYELESGLHEALVERKIKIILIE FTPVTDFTFLPQSLKLLKSHRVLKW KADKSLSYNSRFWKNLLYLMPAKTV KPGRDEPEVLPVLSES | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.