Recombinant Human IL1R2 Protein, Fc-tagged

Specification :
| Description : The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. | Source : HEK293 | Species : Human | Tag : Fc | Form : Lyophilized | Molecular Mass : 64 kDa | Protein Length : 398 | AA Sequence : MLRLYVLVMGVSAFTLQPAAHTGAA RSCRFRGRHYKREFRLEGEPVALRC PQVPYWLWASVSPRINLTWHKNDSA RTVPGEEETRMWAQDGALWLLPALQ EDSGTYVCTTRNASYCDKMSIELRV FENTDAFLPFISYPQILTLSTSGVL VCPDLSEFTRDKTDVKIQWYKDSLL LDKDNEKFLSVRGTTHLLVHDVALE DAGYYRCVLTFAHEGQQYNITRSIE LRIKKKKEETIPVIISPLKTISASL GSRLTIPCKVFLGTGTPLTTMLWWT ANDTHIESAYPGGRVTEGPRQEYSE NNENYIEVPLIFDPVTREDLHMDFK CVVHNTLSFQTLRTTVKEASSTFSW GIVLAPLSLAFLVLGGIWMHRRCKH RTGKADGLTVLWPHHQDFQSYPK | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.