Name :
Recombinant Human IL1R2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Specification :
| Description : The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 45.42 kDa | AA Sequence : MLRLYVLVMGVSAFTLQPAAHTGAA RSCRFRGRHYKREFRLEGEPVALRC PQVPYWLWASVSPRINLTWHKNDSA RTVPGEEETRMWAQDGALWLLPALQ EDSGTYVCTTRNASYCDKMSIELRV FENTDAFLPFISYPQILTLSTSGVL VCPDLSEFTRDKTDVKIQWYKDSLL LDKDNEKFLSVRGTTHLLVHDVALE DAGYYRCVLTFAHEGQQYNITRSIE LRIKKKKEETIPVIISPLKTISASL GSRLTIPCKVFLGTGTPLTTMLWWT ANDTHIESAYPGGRVTEGPRQEYSE NNENYIEVPLIFDPVTREDLHMDFK CVVHNTLSFQTLRTTVKEASSTFSW GIVLAPLSLAFLVLGGIWMHRRCKH RTGKADGLTVLWPHHQDFQSYPKTR TRPLEQKLISEEDLAANDILDYKDD DDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Information :
| Gene Name : IL1R2 interleukin 1 receptor type 2 [ Homo sapiens (human) ] | Official Symbol : IL1R2 | Synonyms : IL1R2; interleukin 1 receptor, type II; IL1RB; interleukin-1 receptor type 2; CD121b; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; antigen CDw121b; IL-1 type II receptor; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; type II interleukin-1 receptor, beta; MGC47725; | Gene ID : 7850 | mRNA Refseq : NM_004633 | Protein Refseq : NP_004624 | MIM : 147811 | UniProt ID : P27930
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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