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Name :
Recombinant Human IL21R protein, His-tagged

Specification :
| Description : IL21R, also known as Interleukin-21 receptor, belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. | Source : Insect cell | Species : Human | Tag : His | Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. | Molecular Mass : 25.6kDa (221aa)28-40KDa (SDS–PAGE under reducing conditions.) | AA Sequence : CPDLVCYTDY LQTVICILEM WNLHPSTLTL TWQDQYEELK DEATSCSLHR SAHNATHATY TCHMDVFHFM ADDIFSVNIT DQSGNYSQECGSFLLAESIK PAPPFNVTVT FSGQYNISWR SDYEDPAFYM LKGKLQYELQ YRNRGDPWAV SPRRKLISVD SRSVSLLPLE FRKDSSYELQVRAGPMPGSS YQGTWSEWSD PVIFQTQSEE LKEVEHHHHH H | Endotoxin : | Purity : >90% by SDS – PAGE | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 1mg/ml (determined by Absorbance at 280nm)

Gene Information :
| Gene Name : IL21R interleukin 21 receptor [ Homo sapiens ] | Official Symbol : IL21R | Synonyms : IL21R; interleukin 21 receptor; interleukin-21 receptor; CD360; IL-21R; IL-21 receptor; novel interleukin receptor; NILR; MGC10967; | Gene ID : 50615 | mRNA Refseq : NM_021798 | Protein Refseq : NP_068570 | MIM : 605383 | UniProt ID : Q9HBE5 | Chromosome Location : 16p11 | Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; | Function : interleukin-21 receptor activity; receptor activity;

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors