Recombinant Human IL2RB Protein

Specification :
| Description : The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq | Source : Wheat Germ | Species : Human | Form : Liquid | Molecular Mass : 61.1 kDa | AA Sequence : MAAPALSWRLPLLILLLPLATSWAS AAVNGTSQFTCFYNSRANISCVWSQ DGALQDTSCQVHAWPDRRRWNQTCE LLPVSQASWACNLILGAPDSQKLTT VDIVTLRVLCREGVRWRVMAIQDFK PFENLRLMAPISLQVVHVETHRCNI SWEISQASHYFERHLEFEARTLSPG HTWEEAPLLTLKQKQEWICLETLTP DTQYEFQVRVKPLQGEFTTWSPWSQ PLAFRTKPAALGKDTIPWLGHLLVG LSGAFGFIILVYLLINCRNTGPWLK KVLKCNTPDPSKFFSQLSSEHGGDV QKWLSSPFPSSSFSPGGLAPEISPL EVLERDKVTQLLLQQDKVPEPASLS SNHSLTSCFTNQGYFFFHLPDALEI EACQVYFTYDPYSEEDPDEGVAGAP TGSSPQPLQPLSGEDDAYCTFPSRD DLLLFSPSLLGGPSPPSTAPGGSGA GEERMPPSLQERVPRDWDPQPLGPP TPGVPDLVDFQPPPELVLREAGEEV PDAGPREGVSFPWSRPPGQGEFRAL NARLPLNTDAYLSLQELQGQDPTHL V | Applications : Antibody ProductionFunctional StudyCompound Screening | Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis. | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.