Name :
Recombinant Human IL2RG, Fc-tagged
Specification :
| Description : The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. | Conjugation : Fc | Form : Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not reco | Purity : >95% by SDS-PAGE | Storage buffer : Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin | Storage : Store at +4°C. | Sequences of amino acids : Theoretical Sequence:LNTTILTPNGNEDTTADFFLTTMPT DSLS VSTLPLPEVQCFVFNVEYMNCTWNS SSEPQPTNLTLHY WYKNSDNDKVQKCSHYLFSEEITSG CQLQKKEIHLYQT FVVQLQDPREPRRQATQMLKLQNLV IPWAPENLTLHKLSESQLELNWNNR FLNHCLEHLVQYRTDWDHSWTEQSV DYR HKFSLPSVDGQKRYTFRVRSRFNPL CGSAQHWSEWSHP IHWGSNTSKENPFLFAWIPKVDKKV EPKSCDKTHTCPP CPAPELLGGPSVFLFPPKPKDTLMI SRTPEVTCVVVDV SHEDPEVKFNWYVDGVEVHNAKTKP REEQYNSTYRVVSVLTVLHQDWLNG KEYKCKVSNKALPAPIEKTISKAKG QPR EPQVYTLPPSRDELTKNQVSLTCLV KGFYPSDIAVEWE SNGQPENNYKTTPPVLDSDGSFFLY SKLTVDKSRWQQG NVFSCSVMHEALHNHYTQKSLSLSP GK
Gene Information :
| Gene Name : IL2RG interleukin 2 receptor, gamma [ Homo sapiens ] | Official Symbol : IL2RG | Synonyms : IL2RG; interleukin 2 receptor, gamma; CIDX, combined immunodeficiency, X linked , IMD4, SCIDX1, severe combined immunodeficiency; cytokine receptor common subunit gamma; CD132; | Gene ID : 3561 | mRNA Refseq : NM_000206 | Protein Refseq : NP_000197 | MIM : 308380 | Uniprot ID : P31785 | Chromosome Location : Xq13 | Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; Endocytosis, organism-specific biosystem; | Function : cytokine receptor activity; interleukin-2 binding; contributes_to interleukin-2 receptor activity; contributes_to interleukin-4 receptor activity; contributes_to interleukin-7 receptor activity;
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