Name :
Recombinant Human IL3RA Protein, His-Avi-tagged, Biotinylated
Specification :
| Description : Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. | Source : HEK293 | Species : Human | Tag : His-Avi | Predicted N Terminal : Thr 19 | Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. | Molecular Mass : The protein has a calculated MW of 36.7 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE). | Protein length : Thr 19 – Arg 305 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >95% as determined by SDS-PAGE. | Storage : For long term storage, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles.This product is stable after storage at:-20°C to -70°C for 12 months in lyophilized state;-70°C for 3 months under sterile conditions after reconstitution. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Information :
| Gene Name : IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ] | Official Symbol : IL3RA | Synonyms : IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; CD123 antigen; CD123; hIL3Ra; hIL-3Ra; MGC34174; IL-3 R alpha | Gene ID : 3563 | mRNA Refseq : NM_002183 | Protein Refseq : NP_002174 | MIM : 308385 | UniProt ID : P26951
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