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Name :
Recombinant Human IL3RA Protein (Met1-Arg305), C-His tagged

Specification :
| Description : Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. | Source : Mammalian cells | Species : Human | Tag : C-His | Form : Lyophilized powder/frozen liquid | Molecular Mass : 33.55 kDa | Protein Length : Met1-Arg305 | Endotoxin : | Purity : >90% as determined by SDS-PAGE. | Notes : For research use only. | Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. | Storage Buffer : Supplied as solution form in PBS or lyophilized from PBS. | Reconstitution : Reconstitute in sterile water for a stock solution. | Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information :
| Gene Name : IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens (human) ] | Official Symbol : IL3RA | Synonyms : IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174; | Gene ID : 3563 | mRNA Refseq : NM_002183 | Protein Refseq : NP_002174 | MIM : 308385 | UniProt ID : P26951

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors