Name :
Recombinant Human IL3RA Protein (Met1-Arg305), C-His tagged
Specification :
| Description : Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. | Source : Mammalian cells | Species : Human | Tag : C-His | Form : Lyophilized powder/frozen liquid | Molecular Mass : 33.55 kDa | Protein Length : Met1-Arg305 | Endotoxin : | Purity : >90% as determined by SDS-PAGE. | Notes : For research use only. | Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. | Storage Buffer : Supplied as solution form in PBS or lyophilized from PBS. | Reconstitution : Reconstitute in sterile water for a stock solution. | Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Information :
| Gene Name : IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens (human) ] | Official Symbol : IL3RA | Synonyms : IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174; | Gene ID : 3563 | mRNA Refseq : NM_002183 | Protein Refseq : NP_002174 | MIM : 308385 | UniProt ID : P26951
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