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Name :
Recombinant Human IL3RA protein, T7/His-tagged

Specification :
| Source : E. coli | Species : Human | Tag : T7/His | Form : 0.2 mg/ml in sterile-filtered solution in 20 mM Tris, pH 7.5. Proprietary formulation of NaCl , KCl, EDTA, arginine, DTT, and glycerol. | AA Sequence : MASMTGGQQMGRGHHHHHHGNLYFQ GGEFTKEDPNPPITNLRMKAKAQQL TWDLNRNVTDIECVKDADYSMPAVN NSYCQFGAISLCEVTNYTVRVANPP FSTWILFPENSGKPWAGAENLTCWI HDVDFLSCSWAVGPGAPADVQYDLY LNVANRRQQYECLHYKTDAQGTRIG CRFDDISRLSSGSQSSHILVRGRSA AFGIPCTDKFVVFSQIEILTPPNMT AKCNKTHSFMHWKMRSHFNRKFRYE LQIQKRMQPVITEQVRDRTSFQLLN PGTYTVQIRARERVYEFLSAWSTPQ RFECDQEEGANTRAWR | Purity : >90% by SDS-PAGE | Applications : 1. May be used for in vitro CD123 mediated IL3 signaling regulation study with this protein as either coating matrix protein or soluble factor.2. May be used for CD123 protein-protein interaction assay.3. Potential diagnostic biomarker for acute myeloid leukemia and lupus dieases.4. As antigen for specific antibody production. | Storage : Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.

Gene Information :
| Gene Name : IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ] | Official Symbol : IL3RA | Synonyms : IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; M | Gene ID : 3563 | mRNA Refseq : NM_002183 | Protein Refseq : NP_002174 | MIM : 308385 | UniProt ID : P26951 | Chromosome Location : Xp22.3 and Yp13.3 | Pathway : Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; | Function : interleukin-3 receptor activity; receptor activity;

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors