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Name :
Active Recombinant Human IL4R Protein, His & Avi-tagged, Biotinylated

Specification :
| Source : HEK293 | Species : Human | Tag : His & Avi | Predicted N Terminal : Met 26 | Form : Lyophilized from sterile PBS, pH7.4, 10% trehalose. | Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized Human IL-4, Tag Free at 5μg/mL (100 μL/well) can bind Biotinylated Human IL-4 R alpha, His Tag with a linear range of 0.005-0.078 μg/mL. | Molecular Mass : Recombinant Human IL4R Protein has a calculated MW of 26.9 kDa. The protein migrates as 40-53 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation. | Protein length : Met 26 – His 232 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >95% as determined by SDS-PAGE. | Stability : Samples are stable for up to twelve months from date of receipt at -70ºC. | Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information :
| Gene Name : IL4R interleukin 4 receptor [ Homo sapiens ] | Official Symbol : IL4R | Synonyms : IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA; | Gene ID : 3566 | mRNA Refseq : NM_000418 | Protein Refseq : NP_000409 | MIM : 147781 | UniProt ID : P24394 | Chromosome Location : 16p12.1-p11.2 | Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-4 signaling Pathway, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; Inflammatory Response Pathway, organism-specific biosystem; | Function : insulin receptor substrate binding; interleukin-4 receptor activity; protein binding; receptor activity; receptor signaling protein activity;

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors