Recombinant Human IL5 protein, His-Avi-tagged, Biotinylated

Specification :
| Description : IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. | Molecular Mass : 18-24kDa, reducing conditions. | Protein length : Ile20-Ser134 | Endotoxin : Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. | Purity : Greater than 95% as determined by reducing SDS-PAGE. | Storage : Lyophilized protein should be stored at Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at | Reconstitution : Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. | Shipping : The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.