Name :
Recombinant Human IL6R, Fc-tagged
Specification :
| Description : Interleukin-6 (IL-6) is a multifunctional factor, which exerts its activities through binding to a highaffinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6Ralpha;) and a signal transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for highaffinity binding of IL-6 by the complex. A soluble form of the IL-6Rα has been found in the urine of healthy adult humans. | Source : CHO Cells | Species : Human | Tag : Fc | Form : Lyophilized from 0.2μm-filtered solution in PBS. | Purity : ≥98% (SDS-PAGE) | Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. | Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles.
Gene Information :
| Gene Name : IL6R interleukin 6 receptor [ Homo sapiens ] | Official Symbol : IL6R | Synonyms : IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1; MGC104991; | Gene ID : 3570 | mRNA Refseq : NM_000565 | Protein Refseq : NP_000556 | MIM : 147880 | UniProt ID : P08887 | Chromosome Location : 1q21 | Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-6 Signaling Pathway, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; | Function : ciliary neurotrophic factor binding; contributes_to ciliary neurotrophic factor receptor activity; enzyme binding; interleukin-6 binding; contributes_to interleukin-6 receptor activity; contributes_to interleukin-6 receptor binding; protein binding; protein homodimerization activity; receptor activity;
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