Share this post on:

Name :
Recombinant Human IL6R protein, His-Avi-tagged

Specification :
| Description : The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha ) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22um filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 41.4 kDa.Due to glycosylation, the protein migrates to 65- 78KDa based on Bis-Tris PAGE result. | Protein length : It contains Leu 20 – Pro 365. | Endotoxin : Less than 0.01EU per ug by the LAL method | Purity : > 95% as determined by SDS-PAGE; > 94% as determined by HPLC | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information :
| Gene Name : IL6R interleukin 6 receptor [ Homo sapiens ] | Official Symbol : IL6R | Synonyms : CD126; gp80; IL-6 R alpha; IL6Q; IL6R alpha; IL-6R alpha; IL6R; IL-6R-1; IL6RA; IL-6Ra; IL6RQ; interleukin 6 receptor1 | Gene ID : 3570 | mRNA Refseq : NM_000565 | Protein Refseq : NP_000556 | MIM : 147880 | UniProt ID : P08887

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
NCAM-1/CD56 Proteinweb
CD55/DAF Proteincustom synthesis
Popular categories:
Ubiquitin-Conjugating Enzyme E2 D1
Testicular Receptor 4

Share this post on:

Author: Cholesterol Absorption Inhibitors