Name :
Recombinant Human IL6R protein, His-Avi-tagged
Specification :
| Description : The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha ) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22um filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 41.4 kDa.Due to glycosylation, the protein migrates to 65- 78KDa based on Bis-Tris PAGE result. | Protein length : It contains Leu 20 – Pro 365. | Endotoxin : Less than 0.01EU per ug by the LAL method | Purity : > 95% as determined by SDS-PAGE; > 94% as determined by HPLC | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Information :
| Gene Name : IL6R interleukin 6 receptor [ Homo sapiens ] | Official Symbol : IL6R | Synonyms : CD126; gp80; IL-6 R alpha; IL6Q; IL6R alpha; IL-6R alpha; IL6R; IL-6R-1; IL6RA; IL-6Ra; IL6RQ; interleukin 6 receptor1 | Gene ID : 3570 | mRNA Refseq : NM_000565 | Protein Refseq : NP_000556 | MIM : 147880 | UniProt ID : P08887
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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