Active Recombinant Human HAVCR2, MIgG2a Fc-tagged

Specification :
| Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins.CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokinesecretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-typehypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infectionsand the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein thatregulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotesimmunological tolerance. | Source : CHO cells | Species : Human | Tag : MIgG2a Fc-tagged | Form : Lyophilized from 0.2μm-filtered solution in PBS. | Bio-activity : Measured by its binding ability in a functional ELISA. | Molecular Mass : 48 KDa (monomer) | AA Sequence : Ser22-Arg200 | Endotoxin : | Purity : >98%, by SDS-PAGE under reducing conditions | Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. | Reconstitution : Reconstitute at 100μg/ml in sterile PBS. | Warning : Avoid freeze/thaw cycles.