Name :
Recombinant Human Integrin, Alpha M (Complement Component 3 Receptor 3 Subunit)
Specification :
| Cat. No. : ITGAM-4257H | Description : Leukocyte associated protein consists of two polypeptide chains with molecular weights 95 and 170kDa. The moleculae functions as a cell surface receptor for the C3bi complement fragment. It belongs to family of heterodimeric proteins (designated CD11) which share a common beta chain CD18 of 95kDa. The alpha chain component of the leukocyte associated antigen is expressed on granulocytes, monocytes and macrophages. | Source : Human | Host : Escherichia Coli. | Form : CD11b in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. | Physical Appearance : Sterile Filtered clear solution. | Storage : Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
Gene Information :
| Gene Name : ITGAM integrin, alpha M (Complement Component 3 receptor 3 subunit) [ Homo sapiens ] | Official Symbol : ITGAM | Synonyms : ITGAM; integrin, alpha M (Complement Component 3 receptor 3 subunit); CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; MGC117044; integrin alpha M; antigen CD11b (p170); macrophage antigen alpha polypeptide; neutrophil adherence receptor alpha-M subunit; CD11b; CD11 antigen-like family member B; CD11b antigen; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; integrin, alpha M (Complement Component 3 receptor 3 subunit); integrin, alpha M (complement component receptor 3, alpha; CD11b (p170), macrophage antigen alpha polypeptide); Integrin alpha-M | Gene ID : 3684 | mRNA Refseq : NM_000632 | Protein Refseq : NP_000623 | MIM : 120980 | UniProt ID : P11215 | Chromosome Location : 16p11.2 | Pathway : Cell adhesion molecules (CAMs); Hematopoietic cell lineage; Leukocyte transendothelial migration; Regulation of actin cytoskeleton | Function : calcium ion binding; glycoprotein binding; heparan sulfate proteoglycan binding; heparin binding; magnesium ion binding; opsonin binding; protein heterodimerization activity; receptor activity
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