Recombinant Human IFNGR1, Fc-tagged

Specification :
| Description : This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. | Conjugation : Fc | Biological activity : The ED50 of IFNGR1 (Fc Chimera) is typically 0.05-0.1 μg/ml as measured by its ability to neutralize IFN gamma mediated cytotoxicity using the HT-29 colorectal adenocarcinoma cell line. | Form : Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not reco | Purity : >95% by SDS-PAGE | Storage buffer : Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin | Storage : Store at +4°C. | Sequences of amino acids : Theoretical sequence: EMGTADLGPSSVPTPTNVTIESYNM NPIVYWEYQIMPQ VPVFTVEVKNYGVKNSEWIDACINI SHHYCNISDHVGD PSNSLWVRVKARVGQKESAYAKSEE FAVCRDGKIGPPK LDIRKEEKQIMIDIFHPSVFVNGDE QEVDYDPETTCYI RVYNVYVRMNGSEIQYKILTQKEDD CDEIQCQLAIPVSSLNSQYCVSAEG VLHVWGVTTEKSKEVCITIFNSSIK GGS SNTKVDKKVEPKSCDKTHTCPPCPA PELLGGPSVFLFP PKPKDTLMISRTPEVTCVVVDVSHE DPEVKFNWYVDGV EVHNAKTKPREEQYNSTYRVVSVLT VLHQDWLNGKEYK CKVSNKALPAPIEKTISKAKGQPRE PQVYTLPPSRDELTKNQVSLTCLVK GFYPSDIAVEWESNGQPENNYKTTP PVL DSDGSFFLYSKLTVDKSRWQQGNVF SCSVMHEALHNHY TQKSLSLSPGK | Sequence Similarities : Belongs to the type II cytokine receptor family.Contains 2 fibronectin type-III domains.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.