Recombinant Human IGF1R protein, DDK/His-tagged

Specification :
| Description : This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : DDK/His | Form : 1 x PBS, pH7.4, 10% glycerol | Molecular Mass : 25 kDa | Protein length : Asp741-His935 | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Concentration : >50 ug/mL as determined by microplate BCA method