Recombinant Human IL1R2 Protein (ECD), Fc-His-tagged(C-ter)

Specification :
| Description : The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012] | Source : HEK293 | Species : Human | Tag : Fc-His(C-ter) | Form : Powder | Protein Length : Met1-Glu343 | Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. | Purity : > 97% (by SDS-PAGE) | Applications : Binding, SDS-PAGE | Notes : For laboratory research only, not for drug, diagnostic or other use. | Storage : Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. | Storage Buffer : PBS (pH 7.4) | Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.