Recombinant Human IL6R Protein, Leu20-Pro365, C-His-Avi tagged, Biotinylated

Specification :
| Description : This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. | Source : HEK293 | Species : Human | Tag : C-His-Avi | Protein length : Leu20-Pro365 | Conjugation/Label : Biotin | Form : Lyophilised | Endotoxin : Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). | Notes : FOR RESEARCH USE ONLY (RUO). | Storage : The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade. | Storage Buffer : Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM