Active Recombinant Human HAVCR2 Protein, Fc-Tagged

Specification :
| Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. | Source : Mouse myeloma cell line | Species : Human | Tag : Fc | Form : Lyophilized | Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Galectin‑9 at 500 ng/mL can bind Recombinant Human TIM-3 Fc Chimera with an apparent Kd | Molecular Mass : 46.4 kDa (monomer) | N-terminal Sequence Analysis : Ser22 | Endotoxin : | Purity : >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. | Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.3 months, -20 to -70 °C under sterile conditions after reconstitution. | Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS. | Reconstitution : Reconstitute at 100 μg/mL in sterile PBS. | Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.