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Name :
Active Recombinant Human HAVCR2 protein, Fc-tagged

Specification :
| Source : HEK293 | Species : Human | Tag : Fc | Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant. | Bio-activity : Immobilized Human TIM-3 (22-200) Protein, Fc Tag at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human TIM-3 Antibody, Human IgG4 with a linear range of 0.2-2 ng/mL. | Molecular Mass : This protein carries a human IgG1 Fc tag at the C-terminusThe protein has a calculated MW of 46.5 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. | Proteinlength : Ser22-Arg200 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >85% as determined by SDS-PAGE. >90% as determined by SEC-MALS. | Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information :
| Gene Name : HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens ] | Official Symbol : HAVCR2 | Synonyms : HAVCR2; hepatitis A virus cellular receptor 2; FLJ14428; Tim 3; TIM3; TIMD3; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; KIM-3; Tim-3; TIMD-3; HAVcr-2; | Gene ID : 84868 | mRNA Refseq : NM_032782 | Protein Refseq : NP_116171 | MIM : 606652 | UniProt ID : Q8TDQ0

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors