Recombinant Human CD47 Protein, Alexa Fluor 555 conjugated

Specification :
| Description : CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus. | Source : HEK293 | Species : Human | Tag : LEVLFQ | Form : Lyophilized | Molecular Mass : 14.5 kDa | Protein length : Met1-Pro139, 128 | N-terminal Sequence Analysis : Gln 19 | Endotoxin : | Purity : > 90 % as determined by SDS-PAGE | Characteristic : Disulfide-linked homodimerLabeled with Alexa Fluor 555 via aminesWith an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters. | Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade. | Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Storage Buffer : Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. | Shipping : Shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.