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Name :
Recombinant Human EGFR Protein, His-tagged

Specification :
| Description : The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). | Source : NS0 | Species : Human | Tag : His | Form : Lyophilized from a 0.2 μm filtered solution in PBS. | Molecular Mass : Predicted Molecular Mass: 39 kDa SDS-PAGE: 65-80 kDa, reducing conditions | N-terminal Sequence Analysis : Leu25 | Endotoxin : | Purity : >95% | Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. | Reconstitution : Reconstitute at 250 μg/mL in PBS. | Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Gene Information :
| Gene Name : EGFR epidermal growth factor receptor [ Homo sapiens (human) ] | Official Symbol : EGFR | Synonyms : ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2 | Gene ID : 1956 | mRNA Refseq : NM_001346941 | Protein Refseq : NP_001333870 | MIM : 131550 | UniProt ID : P00533

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Cholesterol Absorption Inhibitors