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Name :
Recombinant Human EIF2AK1 Protein, GST-tagged

Specification :
| Description : The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 97.5 kDa | AA Sequence : MQGGNSGVRKREEEGDGAGAVAAPP AIDFPAEGPDPEYDESDVPAEIQVL KEPLQQPTFPFAVANQLLLVSLLEH LSHVHEPNPLRSRQVFKLLCQTFIK MGLLSSFTCSDEFSSLRLHHNRAIT HLMRSAKERVRQDPCEDISRIQKIR SREVALEAQTSRYLNEFEELAILGK GGYGRVYKVRNKLDGQYYAIKKILI KGATKTVCMKVLREVKVLAGLQHPN IVGYHTAWIEHVHVIQPRADRAAIE LPSLEVLSDQEEDREQCGVKNDESS SSSIIFAEPTPEKEKRFGESDTENQ NNKSVKYTTNLVIRESGELESTLEL QENGLAGLSASSIVEQQLPLRRNSH LEESFTSTEESSEENVNFLGQTEAQ YHLMLHIQMQLCELSLWDWIVERNK RGREYVDESACPYVMANVATKIFQE LVEGVFYIHNMGIVHRDLKPRNIFL HGPDQQVKIGDFGLACTDILQKNTD WTNRNGKRTPTHTSRVGTCLYASPE QLEGSEYDAKSDMYSLGVVLLELFQ PFGTEMERAEVLTGLRTGQLPESLR KRCPVQAKYIQHLTRRNSSQRPSAI QLLQSELFQNSGNVNLTLQMKIIEQ EKEIAELKKQLNLLSQDKGVRDDGK DGGVG | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 [ Homo sapiens ] | Official Symbol : EIF2AK1 | Synonyms : EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1; heme regulated initiation factor 2 alpha kinase; HRI; KIAA1369; heme-regulated inhibitor; heme-regulated repressor; heme-controlled repressor; heme sensitive initiation factor 2a kinase; heme-regulated initiation factor 2-alpha kinase; hemin-sensitive initiation factor 2-alpha kinase; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; HCR; | Gene ID : 27102 | mRNA Refseq : NM_001134335 | Protein Refseq : NP_001127807 | MIM : 613635 | UniProt ID : Q9BQI3

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors