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Name :
Active Recombinant Human ERBB3(Met1-Thr643), mFc-tagged

Specification :
| Source : HEK293 | Species : Human | Tag : C-mFc | Protein length : Met1-Thr643 | Form : Lyophilized from sterile PBS, pH 7.4. | Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized human ErbB3-mFc at 10 μg/ml (100 μl/well) can bind biotinylated human NRG1, The EC50 of biotinylated human NRG1 is 0.58-1.25 μg/ml. | Molecular Mass : The recombinant human ErbB3/mFc is a disulfide-linked homodimer. The reduced monomer comprises 858 amino acids and has a predicted molecular mass of 95 kDa. The apparent molecular mass of the protein is approximately 119-129 in SDS-PAGE under reducing conditions. | Endotoxin : | Purity : > 95 % as determined by SDS-PAGE. | Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information :
| Gene Name : ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [ Homo sapiens ] | Official Symbol : ERBB3 | Synonyms : ERBB3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); LCCS2, lethal congenital contracture syndrome 2; receptor tyrosine-protein kinase erbB-3; HER3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; MGC88033 | Gene ID : 2065 | mRNA Refseq : NM_001005915 | Protein Refseq : NP_001005915 | MIM : 190151 | UniProt ID : P21860

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Author: Cholesterol Absorption Inhibitors